KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
28.79
Human Site:
Y578
Identified Species:
52.78
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
Y578
K
K
F
I
D
P
I
Y
Q
V
W
E
D
M
S
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
M540
L
Q
E
F
K
K
P
M
K
K
D
I
V
E
D
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
Y578
K
K
F
I
D
P
I
Y
Q
I
W
E
D
M
S
Dog
Lupus familis
XP_536965
651
74211
Y578
K
K
F
I
D
P
V
Y
Q
I
W
E
D
M
N
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
Y576
K
K
F
I
D
P
I
Y
Q
I
W
E
D
G
S
Rat
Rattus norvegicus
NP_001129318
661
75125
Y581
K
K
F
I
D
P
V
Y
Q
A
W
E
D
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
Y587
K
K
I
I
D
P
F
Y
Q
I
W
E
E
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
Y542
K
K
L
M
D
P
F
Y
Q
I
W
E
E
S
N
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
Y542
G
K
L
I
E
P
I
Y
Q
V
W
E
E
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
Q552
E
T
N
Y
M
V
Y
Q
S
N
D
T
D
E
Y
Honey Bee
Apis mellifera
XP_001122533
483
56793
L429
E
N
N
T
R
N
Q
L
P
L
F
D
S
K
K
Nematode Worm
Caenorhab. elegans
P48322
654
75091
W590
T
L
T
K
A
L
C
W
N
A
A
T
A
D
K
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
C320
L
Y
R
H
W
E
G
C
K
P
D
F
S
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
0
93.3
80
N.A.
86.6
86.6
N.A.
66.6
N.A.
53.3
66.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
80
80
N.A.
13.3
26.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
16
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
54
0
0
0
0
0
24
8
47
8
8
% D
% Glu:
16
0
8
0
8
8
0
0
0
0
0
62
24
16
0
% E
% Phe:
0
0
39
8
0
0
16
0
0
0
8
8
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
54
0
0
31
0
0
39
0
8
0
0
0
% I
% Lys:
54
62
0
8
8
8
0
0
16
8
0
0
0
8
16
% K
% Leu:
16
8
16
0
0
8
0
8
0
8
0
0
0
8
8
% L
% Met:
0
0
0
8
8
0
0
8
0
0
0
0
0
31
0
% M
% Asn:
0
8
16
0
0
8
0
0
8
8
0
0
0
0
16
% N
% Pro:
0
0
0
0
0
62
8
0
8
8
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
8
8
62
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
16
8
47
% S
% Thr:
8
8
8
8
0
0
0
0
0
0
0
16
0
0
0
% T
% Val:
0
0
0
0
0
8
16
0
0
16
0
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
8
0
0
62
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
8
62
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _